Stay updated with the latest findings and advancements from our research lab

Keep informed about how our work is shaping the future of respiratory health care.

Year:
2024
Deep immune profiling of chronic rhinosinusitis in allergic and non-allergic cohorts using mass cytometry
Researchers
Kidane, F. A., Muller, L., Rocha-Hasler, M., Tu, A., Stanek, V., Campion, N., Bartosik, T., Zghaebi, M., Stoshikj, S., Gompelmann, D., Spittler, A., Idzko, M., Eckl-Dorna, J., & Schneider, S.
Reference
Clin Immunol, 110174. doi:10.1016/j.clim.2024.110174
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Year:
2023
The nasal microbiome in patients suffering from non-steroidal anti-inflammatory drugs-exacerbated respiratory disease in absence of corticosteroids
Researchers
Bartosik, T. J., Campion, N. J., Freisl, K., Liu, D. T., Gangl, K., Stanek, V., Tu, A., Pjevac, P., Hausmann, B., Eckl-Dorna, J., & Schneider, S.
Reference
Front Immunol, 14, 1112345. doi:10.3389/fimmu.2023.1112345
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Year:
2023
Nasal IL-13 production identifies patients with late phase allergic responses
Researchers
Campion, N. J., Villazala-Merino, S., Thwaites, R. S., Stanek, V., Fd, H. K., Pertsinidou, E., Zghaebi, M., Toth, J., Froschl, R., Perkmann, T., Gangl, K., Schneider, S., Ristl, R., Scott, I. C., Cohen, E. S., Molin, M., Focke-Tejkl, M., Regelsberger, G., Hansel, T. T., Valenta, R., Eckl-Dorna, J., & Niederberger-Leppin, V.
Reference
J Allergy Clin Immunol. doi:10.1016/j.jaci.2023.06.026
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Year:
2024
Patient-reported disease control versus overall symptom severity as global metrics of chronic rhinosinusitis disease status.
Researchers
Cotter, R.A., Garcia, J.T., Alsayed A, Schneider, S., Liu, D.T., Eckl-Dorna, J., Houssein, F.A., Boparai, R.S., Parail, N.A., Chu, M.M., Meier, J.C., Alsaleh, S., Phillips, K.M., & Sedaghat, A.R.
Reference
Int Forum Allergy Rhinol, Online ahead of print. doi: 10.1002/alr.23435.
Year:
2024
Modulation of Bronchial Epithelial Barrier Integrity by Low Molecular Weight Components from Birch Pollen
Researchers
Sudharson, S., Kalic, T., Eckl-Dorna, J., Lengger, N., Breiteneder, H., & Hafner C.
Reference
Int J Mol Sci, 25(13):7374. doi: 10.3390/ijms25137374.
Year:
2024
Overall symptom severity as a patient-reported outcome measure for chronic rhinosinusitis: what it reflects and how to measure it
Researchers
Garcia, J.T., Cotter, R.A., Boparai, R.S., Alsayed, A., Schneider, S., Liu, D.T., Eckl-Dorna, J., Parail, N.A., Houssein, F.A., Chu, M.M., Meier, J.C., Alsaleh, S., Phillips, K.M., & Sedaghat, A.R.
Reference
Rhinology, online ahead of print. doi: 10.4193/Rhin24.145.
Year:
2024
Trimeric Bet v 1-specific nanobodies cause strong suppression of IgE binding
Researchers
Bauernfeind, C., Zettl, I., Ivanova, T., Goryainova, O., Weijler, A.M., Pranz, B., Drescher, A., Focke-Tejkl, M., Pavkov-Keller, T., Eckl-Dorna, J., Tillib, S.V.,& Flicker, S.
Reference
Front Immunol, 15:1343024. doi: 10.3389/fimmu.2024.1343024. eCollection 2024
Year:
2024
Real-Life Study of Patient Preference for Dupilumab or Revision Surgery for Recurrent Chronic Rhinosinusitis with Nasal Polyps
Researchers
Gangl, K., Liu, D. T., Bartosik, T., Campion, N. J., Vyskocil, E., Mueller, C. A., Knerer, B., Eckl-Dorna, J., & Schneider, S.
Reference
J Pers Med, 14(4). doi:10.3390/jpm14040338
Year:
2024
Deep immune profiling of chronic rhinosinusitis in allergic and non-allergic cohorts using mass cytometry
Researchers
Kidane, F. A., Muller, L., Rocha-Hasler, M., Tu, A., Stanek, V., Campion, N., Bartosik, T., Zghaebi, M., Stoshikj, S., Gompelmann, D., Spittler, A., Idzko, M., Eckl-Dorna, J., & Schneider, S.
Reference
Clin Immunol, 110174. doi:10.1016/j.clim.2024.110174
Year:
2024
Coupling of a Major Allergen to the Surface of Immune Cells for Use in Prophylactic Cell Therapy for the Prevention of IgE-Mediated Allergy
Researchers
Mengrelis, K., Niederacher, G., Prickler, L., Kainz, V., Weijler, A. M., Rudolph, E., Stanek, V., Eckl-Dorna, J., Baranyi, U., Spittler, A., Focke-Tejkl, M., Bohle, B., Valenta, R., Becker, C. F. W., Wekerle, T., & Linhart, B.
Reference
Cells, 13(5). doi:10.3390/cells13050446
Year:
2023
The nasal microbiome in patients suffering from non-steroidal anti-inflammatory drugs-exacerbated respiratory disease in absence of corticosteroids
Researchers
Bartosik, T. J., Campion, N. J., Freisl, K., Liu, D. T., Gangl, K., Stanek, V., Tu, A., Pjevac, P., Hausmann, B., Eckl-Dorna, J., & Schneider, S.
Reference
Front Immunol, 14, 1112345. doi:10.3389/fimmu.2023.1112345
Year:
2023
Efficacy and safety of switching between biologics in chronic rhinosinusitis with nasal polyps or N-ERD
Researchers
Brkic, F. F., Liu, D. T., Klimbacher, R., Campion, N. J., Bartosik, T. J., Vyskocil, E., Stanek, V., Tu, A., Arnoldner, T., Bangert, C., Gangl, K., Eckl-Dorna, J., & Schneider, S.
Reference
Rhinology, 61(4), 320-327. doi:10.4193/Rhin22.408
Year:
2023
The "real life" efficacy of dupilumab is independent of initial polyp size and concomitant steroids in CRSwNP
Researchers
Campion, N. J., Brugger, J., Tu, A., Stanek, V., Brkic, F. F., Bartosik, T. J., Liu, D. T., Hoehl, B. S., Gangl, K., Eckl-Dorna, J., & Schneider, S.
Reference
J Otolaryngol Head Neck Surg, 52(1), 56. doi:10.1186/s40463-023-00663-4
Year:
2023
Dupilumab reduces symptom burden in allergic rhinitis and suppresses allergen-specific IgE production
Researchers
Campion, N. J., Doralt, A., Lupinek, C., Berger, M., Poglitsch, K., Brugger, J., Quint, T., Gangl, K., Sinz, C., Bartosik, T., Liu, D. T., Landegger, L. D., Tu, A., Stanek, V., Berger, U., Bangert, C., Schneider, S., & Eckl-Dorna, J.
Reference
Allergy. doi:10.1111/all.15653
Year:
2023
Nasal IL-13 production identifies patients with late phase allergic responses
Researchers
Campion, N. J., Villazala-Merino, S., Thwaites, R. S., Stanek, V., Fd, H. K., Pertsinidou, E., Zghaebi, M., Toth, J., Froschl, R., Perkmann, T., Gangl, K., Schneider, S., Ristl, R., Scott, I. C., Cohen, E. S., Molin, M., Focke-Tejkl, M., Regelsberger, G., Hansel, T. T., Valenta, R., Eckl-Dorna, J., & Niederberger-Leppin, V.
Reference
J Allergy Clin Immunol. doi:10.1016/j.jaci.2023.06.026
Year:
2023
Dupilumab-induced skin-associated side effects in patients with chronic rhinosinusitis with nasal polyposis
Researchers
Chromy, D., Bartosik, T., Brkic, F. F., Quint, T., Tu, A., Eckl-Dorna, J., Schneider, S., & Bangert, C.
Reference
J Dermatol, 50(1), 89-93. doi:10.1111/1346-8138.16595
Year:
2023
Pitfalls in sampling and analyzing low-biomass human nasal microbiome samples
Researchers
Pjevac, P., Bartosik, T., Schneider, S., & Eckl-Dorna, J.
Reference
J Allergy Clin Immunol, 152(1), 304. doi:10.1016/j.jaci.2023.04.001
Year:
2023
Dupilumab increases aspirin tolerance in NSAID-exacerbated respiratory disease.
Researchers
Schneider, S., Poglitsch, K., Morgenstern, C., Quint, T., Gangl, K., Sinz, C., Bartosik, T., Campion, N. J., Liu, D. T., Landegger, L. D., Tu, A., Stanek, V., Rocha-Hasler, M., Bangert, C., & Eckl-Dorna, J.
Reference
Eur Respir J, 61(3). doi:10.1183/13993003.01335-2022
Year:
2023
Chronic Rhinosinusitis Outcome Registry (CHRINOSOR): Establishment of an International Outcome Registry Driven by mHealth Technology
Researchers
Seys, S. F., Hellings, P. W., Alobid, I., Backer, V., Bequignon, E., von Buchwald, C., Cavaliere, C., Coste, A., Deneyer, L., Diamant, Z., Eckl-Dorna, J., Fokkens, W. J., Gane, S., Gevaert, P., Holbaek-Haase, C., Holzmeister, C., Hopkins, C., Hox, V., Huart, C., Jankowski, R., Jorissen, M., Kjeldsen, A., Knipps, L., Lange, B., van der Lans, R., Laulajainen-Hongisto, A., Larsen, K., Liu, D. T., Lund, V., Marien, G., Masieri, S., Mortuaire, G., Mullol, J., Reitsma, S., Rombaux, P., Schneider, S., Steinsvik, A., Tomazic, P. V., Toppila-Salmi, S. K., Van Gerven, L., Van Zele, T., Virkkula, P., Wagenmann, M., & Bachert, C.
Reference
J Allergy Clin Immunol Pract, 11(2), 431-438 e432. doi:10.1016/j.jaip.2022.09.043
Year:
2023
Antibody Conjugates Bispecific for Pollen Allergens and ICAM-1 with Potential to Prevent Epithelial Allergen Transmigration and Rhinovirus Infection
Researchers
Weichwald, C., Zettl, I., Ellinger, I., Niespodziana, K., Waltl, E. E., Villazala-Merino, S., Ivanov, D., Eckl-Dorna, J., Niederberger-Leppin, V., Valenta, R., & Flicker, S.
Reference
Int J Mol Sci, 24(3). doi:10.3390/ijms24032725
Year:
2022
Comprehensive Analysis of Nasal Polyps Reveals a More Pronounced Type 2 Transcriptomic Profile of Epithelial Cells and Mast Cells in Aspirin-Exacerbated Respiratory Disease
Researchers
Bangert, C., Villazala-Merino, S., Fahrenberger, M., Krausgruber, T., Bauer, W. M., Stanek, V., Campion, N. J., Bartosik, T., Quint, T., Regelsberger, G., Niederberger-Leppin, V., Bock, C., Schneider, S., & Eckl-Dorna, J.
Reference
Front Immunol, 13, 850494. doi:10.3389/fimmu.2022.850494
Year:
2022
Chronic rhinosinusitis symptoms differentially impact the likelihood of major depressive disorders.
Researchers
Liu, D. T., Bartosik, T. J., Campion, N. J., Bayer, K., Tu, A., Victoria, S., Besser, G., Mueller, C. A., Gangl, K., Eckl-Dorna, J., & Schneider, S.
Reference
Laryngoscope Investig Otolaryngol, 7(1), 29-35. doi:10.1002/lio2.733
Year:
2022
Annual trends in Google searches provides insights related to rhinosinusitis exacerbations
Researchers
Liu, D. T., Schally, M., Schneider, S., Eckl-Dorna, J., Phillips, K. M., Mueller, C. A., Sedaghat, A. R., & Besser, G.
Reference
Eur Arch Otorhinolaryngol, 279(1), 213-223. doi:10.1007/s00405-021-06806-5
Year:
2022
Using mass cytometry for the analysis of samples of the human airways
Researchers
Rocha-Hasler, M., Muller, L., Wagner, A., Tu, A., Stanek, V., Campion, N. J., Bartosik, T., Zghaebi, M., Stoshikj, S., Gompelmann, D., Zech, A., Mei, H., Kratochwill, K., Spittler, A., Idzko, M., Schneider, S., & Eckl-Dorna, J.
Reference
Front Immunol, 13, 1004583. doi:10.3389/fimmu.2022.1004583
Year:
2022
Identification of apple cultivars hypoallergenic for birch pollen-allergic individuals by a multidisciplinary in vitro and in vivo approach
Researchers
Strobl, M. R., Vollmann, U., Eckl-Dorna, J., Radakovics, A., Ibl, V., Schnurer, M., Brenner, M., Dermendjiev, G., Weckwerth, W., Neumuller, M., Frommlet, F., Demir, H., Bublin, M., Muller, C., & Bohle, B.
Reference
Clin Transl Allergy, 12(8), e12186. doi:10.1002/clt2.12186
Year:
2022
Generation of high affinity ICAM-1-specific nanobodies and evaluation of their suitability for allergy treatment
Researchers
Zettl, I., Ivanova, T., Zghaebi, M., Rutovskaya, M. V., Ellinger, I., Goryainova, O., Kollarova, J., Villazala-Merino, S., Lupinek, C., Weichwald, C., Drescher, A., Eckl-Dorna, J., Tillib, S. V., & Flicker, S.
Reference
Front Immunol, 13, 1022418. doi:10.3389/fimmu.2022.1022418
Year:
2022
Ameliorating Atopy by Compensating Micronutritional Deficiencies in Immune Cells: A Double-Blind Placebo-Controlled Pilot Study
Researchers
Bartosik, T., Jensen, S.A., Afify, S.M., Bianchini, R., Hufnagl, K., Hofstetter, G., Berger, M., Bastl, M., Berger, U., Rivelles, E., Schmetterer, K., Eckl-Dorna, J., Brkic, F.F., Vyskocil, E., Guethoff, S., Graessel, A., Kramer, M.F., Jensen-Jarolim, E., & Roth-Walter, F.
Reference
J Allergy Clin Immunol Pract. 10(7):1889-1902.e9. doi: 10.1016/j.jaip.2022.02.028.
Year:
2021
Preventive Administration of Non-Allergenic Bet v 1 Peptides Reduces Allergic Sensitization to Major Birch Pollen Allergen, Bet v 1
Researchers
Akinfenwa, O., Huang, H. J., Linhart, B., Focke-Tejkl, M., Vrtala, S., Poroshina, A., Nikonova, A., Khaitov, M., Campion, N. J., Eckl-Dorna, J., Niederberger-Leppin, V., Kratzer, B., Tauber, P. A., Pickl, W. F., Kundi, M., Campana, R., & Valenta, R.
Reference
Front Immunol, 12, 744544. doi:10.3389/fimmu.2021.744544
Year:
2021
Differences in men and women suffering from CRSwNP and AERD in quality of life
Researchers
Bartosik, T. J., Liu, D. T., Campion, N. J., Villazala-Merino, S., Janik, S., Dahm, V., Mueller, C. A., Vyskocil, E., Stanek, V., Quint, T., Bangert, C., Eckl-Dorna, J., & Schneider, S.
Reference
Eur Arch Otorhinolaryngol, 278(5), 1419-1427. doi:10.1007/s00405-020-06418-5
Year:
2021
Prevalence and Symptom Burden of Nasal Polyps in a Large Austrian Population
Researchers
Campion, N. J., Kohler, R., Ristl, R., Villazala-Merino, S., Eckl-Dorna, J., & Niederberger-Leppin, V.
Reference
J Allergy Clin Immunol Pract, 9(11), 4117-4129 e4112. doi:10.1016/j.jaip.2021.06.037
Year:
2021
Functional iron-deficiency in women with allergic rhinitis is associated with symptoms after nasal provocation and lack of iron-sequestering microbes
Researchers
Petje, L. M., Jensen, S. A., Szikora, S., Sulzbacher, M., Bartosik, T., Pjevac, P., Hausmann, B., Hufnagl, K., Untersmayr, E., Fischer, L., Vyskocil, E., Eckl-Dorna, J., Jensen-Jarolim, E., Hofstetter, G., Afify, S. M., Krenn, C. G., Roth, G. A., Rivelles, E., Hann, S., & Roth-Walter, F.
Reference
Allergy, 76(9), 2882-2886. doi:10.1111/all.14960
Year:
2021
Tracing Human IgE B Cell Antigen Receptor-Bearing Cells With a Monoclonal Anti-Human IgE Antibody That Specifically Recognizes Non-Receptor-Bound IgE
Researchers
Zghaebi, M., Byazrova, M., Flicker, S., Villazala-Merino, S., Campion, N. J., Stanek, V., Tu, A., Breiteneder, H., Filatov, A., Khaitov, M., Niederberger-Leppin, V., Eckl-Dorna, J., & Valenta, R.
Reference
Front Immunol, 12, 803236. doi:10.3389/fimmu.2021.803236
Year:
2020
Early effects of cigarette smoke extract on human oral keratinocytes and carcinogenesis in head and neck squamous cell carcinoma
Researchers
Foki, E., Gangl, K., Kranebitter, V., Niederberger-Leppin, V., Eckl-Dorna, J., Wiebringhaus, R., Thurnher, D., & Heiduschka, G.
Reference
Head Neck, 42(9), 2348-2354. doi:10.1002/hed.26247
Year:
2020
Highly sensitive ELISA-based assay for quantification of allergen-specific IgE antibody levels
Researchers
Karsonova, A., Riabova, K., Villazala-Merino, S., Campana, R., Niederberger, V., Eckl-Dorna, J., Froschl, R., Perkmann, T., Zhernov, Y. V., Elisyutina, O. G., Fedenko, E. S., Khaitov, M. R., Fomina, D., Beltiukov, E., van Hage, M., Gronlund, H., Valenta, R., Karaulov, A., & Curin, M.
Reference
Allergy, 75(10), 2668-2670. doi:10.1111/all.14325
Year:
2020
A Novel Variant in the TBC1D24 Lipid-Binding Pocket Causes Autosomal Dominant Hearing Loss: Evidence for a Genotype-Phenotype Correlation
Researchers
Parzefall, T., Frohne, A., Koenighofer, M., Neesen, J., Laccone, F., Eckl-Dorna, J., Waters, J. J., Schreiner, M., Amr, S. S., Ashton, E., Schoefer, C., Gstoettner, W., Frei, K., & Lucas, T.
Reference
Front Cell Neurosci, 14, 585669. doi:10.3389/fncel.2020.585669
Year:
2020
Associations between the Quality of Life and Nasal Polyp Size in Patients Suffering from Chronic Rhinosinusitis without Nasal Polyps, with Nasal Polyps or Aspirin-Exacerbated Respiratory Disease
Researchers
Schneider, S., Campion, N. J., Villazala-Merino, S., Liu, D. T., Bartosik, T., Landegger, L. D., Ahmadi, N., Mueller, C. A., Vyskocil, E., Stanek, V., Quint, T., Bangert, C., & Eckl-Dorna, J.
Reference
J Clin Med, 9(4). doi:10.3390/jcm9040925
Year:
2020
Allergen-specific IgE levels and the ability of IgE-allergen complexes to cross-link determine the extent of CD23-mediated T-cell activation
Researchers
Villazala-Merino, S., Rodriguez-Dominguez, A., Stanek, V., Campion, N. J., Gattinger, P., Hofer, G., Froeschl, R., Fae, I., Lupinek, C., Vrtala, S., Breiteneder, H., Keller, W., Perkmann, T., Nakamura, R., Pickl, W. F., Valenta, R., Eckl-Dorna, J., & Niederberger, V.
Reference
J Allergy Clin Immunol, 145(3), 958-967 e955. doi:10.1016/j.jaci.2019.11.019
Year:
2020
Primary Nasal Epithelial Cells From Allergic and Non-allergic Individuals Show Comparable Barrier Function
Researchers
Waltl, E. E., Stanek, V., Mueller, C. A., Kiss, R., Eckl-Dorna, J., Valenta, R., & Niederberger, V.
Reference
Allergy Asthma Immunol Res, 12(2), 364-370. doi:10.4168/aair.2020.12.2.364
Year:
2019
Tracing IgE-Producing Cells in Allergic Patients
Researchers
Eckl-Dorna, J., Villazala-Merino, S., Campion, N. J., Byazrova, M., Filatov, A., Kudlay, D., Karsonova, A., Riabova, K., Khaitov, M., Karaulov, A., Niederberger-Leppin, V., & Valenta, R.
Reference
Cells, 8(9). doi:10.3390/cells8090994
Year:
2019
Allergen-Specific Antibodies Regulate Secondary Allergen-Specific Immune Responses
Researchers
Eckl-Dorna, J., Villazala-Merino, S., Linhart, B., Karaulov, A. V., Zhernov, Y., Khaitov, M., Niederberger-Leppin, V., & Valenta, R.
Reference
Front Immunol, 9, 3131. doi:10.3389/fimmu.2018.03131
Year:
2019
Two years of treatment with the recombinant grass pollen allergy vaccine BM32 induces a continuously increasing allergen-specific IgG4 response
Researchers
Eckl-Dorna, J., Weber, M., Stanek, V., Linhart, B., Ristl, R., Waltl, E. E., Villazala-Merino, S., Hummel, A., Focke-Tejkl, M., Froeschel, R., Neubauer, A., Henning, R., Perkmann, T., Valenta, R., & Niederberger, V.
Reference
EBioMedicine, 50, 421-432. doi:10.1016/j.ebiom.2019.11.006
Year:
2018
Intranasal administration of allergen increases specific IgE whereas intranasal omalizumab does not increase serum IgE levels-A pilot study
Researchers
Eckl-Dorna, J., Froschl, R., Lupinek, C., Kiss, R., Gattinger, P., Marth, K., Campana, R., Mittermann, I., Blatt, K., Valent, P., Selb, R., Mayer, A., Gangl, K., Steiner, I., Gamper, J., Perkmann, T., Zieglmayer, P., Gevaert, P., Valenta, R., & Niederberger, V.
Reference
Allergy, 73(5), 1003-1012. doi:10.1111/all.13343
Year:
2018
Safety and efficacy of immunotherapy with the recombinant B-cell epitope-based grass pollen vaccine BM32
Researchers
Niederberger, V., Neubauer, A., Gevaert, P., Zidarn, M., Worm, M., Aberer, W., Malling, H. J., Pfaar, O., Klimek, L., Pfutzner, W., Ring, J., Darsow, U., Novak, N., Gerth van Wijk, R., Eckl-Dorna, J., Focke-Tejkl, M., Weber, M., Muller, H. H., Klinger, J., Stolz, F., Breit, N., Henning, R., & Valenta, R.
Reference
J Allergy Clin Immunol, 142(2), 497-509 e499. doi:10.1016/j.jaci.2017.09.052
Year:
2018
Molecular Aspects of Allergens and Allergy
Researchers
Valenta, R., Karaulov, A., Niederberger, V., Gattinger, P., van Hage, M., Flicker, S., Linhart, B., Campana, R., Focke-Tejkl, M., Curin, M., Eckl-Dorna, J., Lupinek, C., Resch-Marat, Y., Vrtala, S., Mittermann, I., Garib, V., Khaitov, M., Valent, P., & Pickl, W. F.
Reference
Adv Immunol, 138, 195-256. doi:10.1016/bs.ai.2018.03.002
Year:
2018
Betamethasone prevents human rhinovirus- and cigarette smoke- induced loss of respiratory epithelial barrier function
Researchers
Waltl, E. E., Selb, R., Eckl-Dorna, J., Mueller, C. A., Cabauatan, C. R., Eiwegger, T., Resch-Marat, Y., Niespodziana, K., Vrtala, S., Valenta, R., & Niederberger, V.
Reference
Sci Rep, 8(1), 9688. doi:10.1038/s41598-018-27022-y
Year:
2017
CD23 surface density on B cells is associated with IgE levels and determines IgE-facilitated allergen uptake, as well as activation of allergen-specific T cells
Researchers
Selb, R., Eckl-Dorna, J., Neunkirchner, A., Schmetterer, K., Marth, K., Gamper, J., Jahn-Schmid, B., Pickl, W. F., Valenta, R., & Niederberger, V.
Reference
J Allergy Clin Immunol, 139(1), 290-299 e294. doi:10.1016/j.jaci.2016.03.042
Year:
2017
Critical and direct involvement of the CD23 stalk region in IgE binding
Researchers
Selb, R., Eckl-Dorna, J., Twaroch, T. E., Lupinek, C., Teufelberger, A., Hofer, G., Focke-Tejkl, M., Gepp, B., Linhart, B., Breiteneder, H., Ellinger, A., Keller, W., Roux, K. H., Valenta, R., & Niederberger, V.
Reference
J Allergy Clin Immunol, 139(1), 281-289 e285. doi:10.1016/j.jaci.2016.04.015
Year:
2016
Omalizumab's Impact on Total and Allergen-Specific IgE Levels: A Polyclonal Story
Researchers
Eckl-Dorna, J.
Reference
Int Arch Allergy Immunol, 169(2), 69-70. doi:10.1159/000444998
Year:
2016
Poor association of allergen-specific antibody, T- and B-cell responses revealed with recombinant allergens and a CFSE dilution-based assay
Researchers
Eckl-Dorna, J., Campana, R., Valenta, R., & Niederberger, V.
Reference
Allergy, 70(10), 1222-1229. doi:10.1111/all.12661
Year:
2015
Development and characterization of a recombinant, hypoallergenic, peptide-based vaccine for grass pollen allergy
Researchers
Focke-Tejkl, M., Weber, M., Niespodziana, K., Neubauer, A., Huber, H., Henning, R., Stegfellner, G., Maderegger, B., Hauer, M., Stolz, F., Niederberger, V., Marth, K., Eckl-Dorna, J., Weiss, R., Thalhamer, J., Blatt, K., Valent, P., & Valenta, R.
Reference
J Allergy Clin Immunol, 135(5), 1207-1207 e1201-1211. doi:10.1016/j.jaci.2014.09.012
Year:
2015
Two types of BCR interactions are positively selected during leukemia development in the Emu-TCL1 transgenic mouse model of CLL
Researchers
Iacovelli, S., Hug, E., Bennardo, S., Duehren-von Minden, M., Gobessi, S., Rinaldi, A., Suljagic, M., Bilbao, D., Bolasco, G., Eckl-Dorna, J., Niederberger, V., Autore, F., Sica, S., Laurenti, L., Wang, H., Cornall, R. J., Clarke, S. H., Croce, C. M., Bertoni, F., Jumaa, H., & Efremov, D. G.
Reference
Blood, 125(10), 1578-1588. doi:10.1182/blood-2014-07-587790
Year:
2015
Effect of the coffee ingredient cafestol on head and neck squamous cell carcinoma cell lines
Researchers
Kotowski, U., Heiduschka, G., Seemann, R., Eckl-Dorna, J., Schmid, R., Kranebitter, V., Stanisz, I., Brunner, M., Lill, C., & Thurnher, D.
Reference
Strahlenther Onkol, 191(6), 511-517. doi:10.1007/s00066-014-0807-x
Year:
2015
Antibody conjugates bispecific for intercellular adhesion molecule 1 and allergen prevent migration of allergens through respiratory epithelial cell layers
Researchers
Madritsch, C., Eckl-Dorna, J., Blatt, K., Ellinger, I., Kundi, M., Niederberger, V., Valent, P., Valenta, R., & Flicker, S.
Reference
J Allergy Clin Immunol, 136(2), 490-493 e411. doi:10.1016/j.jaci.2015.01.006
Year:
2015
Skin test evaluation of a novel peptide carrier-based vaccine, BM32, in grass pollen-allergic patients
Researchers
Niederberger, V., Marth, K., Eckl-Dorna, J., Focke-Tejkl, M., Weber, M., Hemmer, W., Berger, U., Neubauer, A., Stolz, F., Henning, R., & Valenta, R.
Reference
J Allergy Clin Immunol, 136(4), 1101-1103 e1108. doi:10.1016/j.jaci.2015.03.034
Year:
2014
Recombinant allergen-based provocation testing
Researchers
Niederberger, V., Eckl-Dorna, J., & Pauli, G
Reference
Methods, 66(1), 96-105. doi:10.1016/j.ymeth.2013.07.037
Year:
2013
What is the source of serum allergen-specific IgE?
Researchers
Eckl-Dorna, J., & Niederberger, V.
Reference
Curr Allergy Asthma Rep, 13(3), 281-287. doi:10.1007/s11882-013-0348-x
Year:
2013
Different modes of IgE binding to CD23 revealed with major birch allergen, Bet v 1-specific monoclonal IgE
Researchers
Reginald, K., Eckl-Dorna, J., Zafred, D., Focke-Tejkl, M., Lupinek, C., Niederberger, V., Keller, W., & Valenta, R.
Reference
Immunol Cell Biol, 91(2), 167-172. doi:10.1038/icb.2012.70
Year:
2013
An assay that may predict the development of IgG enhancing allergen-specific IgE binding during birch immunotherapy
Researchers
Selb, R., Eckl-Dorna, J., Vrtala, S., Valenta, R., & Niederberger, V.
Reference
Allergy, 68(9), 1199-1202. doi:10.1111/all.12204
Year:
2012
Natural killer cell-mediated augmentation of autoantibody production?
Researchers
Eckl-Dorna, J.
Reference
J Leukoc Biol, 92(4), 695-697. doi:10.1189/jlb.0512254
Year:
2012
Basophils are not the key antigen-presenting cells in allergic patients
Researchers
Eckl-Dorna, J., Ellinger, A., Blatt, K., Ghanim, V., Steiner, I., Pavelka, M., Valent, P., Valenta, R., & Niederberger, V.
Reference
Allergy, 67(5), 601-608. doi:10.1111/j.1398-9995.2012.02792.x
Year:
2012
The majority of allergen-specific IgE in the blood of allergic patients does not originate from blood-derived B cells or plasma cells
Researchers
Eckl-Dorna, J., Pree, I., Reisinger, J., Marth, K., Chen, K. W., Vrtala, S., Spitzauer, S., Valenta, R., & Niederberger, V.
Reference
Clin Exp Allergy, 42(9), 1347-1355. doi:10.1111/j.1365-2222.2012.04030.x
Year:
2011
Staphylococcus aureus fibronectin-binding protein specifically binds IgE from patients with atopic dermatitis and requires antigen presentation for cellular immune responses
Researchers
Reginald, K., Westritschnig, K., Linhart, B., Focke-Tejkl, M., Jahn-Schmid, B., Eckl-Dorna, J., Heratizadeh, A., Stocklinger, A., Balic, N., Spitzauer, S., Niederberger, V., Werfel, T., Thalhamer, J., Weidinger, S., Novak, N., Ollert, M., Hirschl, A. M., & Valenta, R.
Reference
J Allergy Clin Immunol, 128(1), 82-91 e88. doi:10.1016/j.jaci.2011.02.034
Year:
2010
Exposure of rye (Secale cereale) cultivars to elevated ozone levels increases the allergen content in pollen
Researchers
Eckl-Dorna, J., Klein, B., Reichenauer, T. G., Niederberger, V., & Valenta, R.
Reference
J Allergy Clin Immunol, 126(6), 1315-1317. doi:10.1016/j.jaci.2010.06.012
Year:
2009
BCR-mediated uptake of antigen linked to TLR9 ligand stimulates B-cell proliferation and antigen-specific plasma cell formation.
Researchers
Eckl-Dorna, J., & Batista, F. D.
Reference
Blood, 113(17), 3969-3977. doi:10.1182/blood-2008-10-185421
Year:
2008
B cell receptor-mediated uptake of CD1d-restricted antigen augments antibody responses by recruiting invariant NKT cell help in vivo
Researchers
Barral, P., Eckl-Dorna, J., Harwood, N. E., De Santo, C., Salio, M., Illarionov, P., Besra, G. S., Cerundolo, V., & Batista, F. D.
Reference
Proc Natl Acad Sci U S A, 105(24), 8345-8350. doi:10.1073/pnas.0802968105
Year:
2007
The role of integrins and coreceptors in refining thresholds for B-cell responses
Researchers
Batista, F. D., Arana, E., Barral, P., Carrasco, Y. R., Depoil, D., Eckl-Dorna, J., Fleire, S., Howe, K., Vehlow, A., Weber, M., & Treanor, B.
Reference
Immunol Rev, 218, 197-213. doi:10.1111/j.1600-065X.2007.00540.x